Pharmacological Treatment for Hepatopulmonary Syndrome
Aim. Hepatopulmonary syndrome is a pulmonary dysfunction in the context of liver cirrhosis characterized by arterial deoxygenation. Affected patients have increased morbidity and mortality, and many of...
View ArticleAn Update on Laboratory Diagnosis of Liver Inherited Diseases
Liver inherited diseases are a group of genetically determined clinical entities that appear with an early chronic liver involvement. They include Wilson’s disease (hepatolenticular degeneration),...
View ArticleAlbumin Reduces Paracentesis-Induced Circulatory Dysfunction and Reduces...
Background. Studies have suggested that albumin has a value in cirrhotic patients undergoing paracentesis but its value in infection and sepsis is less clear. We planned to perform a meta-analysis of...
View ArticleRole of the Microbiota and Antibiotics in Primary Sclerosing Cholangitis
Primary sclerosing cholangitis (PSC) is an idiopathic, progressive, cholestatic liver disease with considerable morbidity and mortality and no established pharmacotherapy. In addition to the...
View Article5-Lipoxygenase Deficiency Reduces Acetaminophen-Induced Hepatotoxicity and...
5-Lipoxygenase (5-LO) converts arachidonic acid into leukotrienes (LTs) and is involved in inflammation. At present, the participation of 5-LO in acetaminophen (APAP)-induced hepatotoxicity and liver...
View ArticleThe Role of Bone Marrow Mesenchymal Stem Cells in the Treatment of Acute...
Objective. This study is to investigate the effects of bone marrow mesenchymal stem cell (BMSC) transplantation on acute liver failure (ALF). Methods. BMSCs were separated from rat bone marrow,...
View ArticleAmelioration of Prallethrin-Induced Oxidative Stress and Hepatotoxicity in...
This study was carried out to evaluate the adverse effects of exposure to prallethrin on oxidant/antioxidant status and liver dysfunction biomarkers and the protective role of Origanum majorana...
View ArticleProfiling of Hepatocellular Carcinoma Cell Cycle Regulating Genes Targeted by...
We cocultured calycosin with human hepatocellular carcinoma cell line (BEL-7402) to investigate the effect on cell proliferation. Calycosin can markedly block the cell growth in G1 phase () on the IC50...
View ArticleClinical Significance of AFP and PIVKA-II Responses for Monitoring Treatment...
Aim. Recently, the utility of tumor markers in the hepatocellular carcinoma (HCC) field has received a good deal of attention. Here, we review and summarize the results of studies on the roles played...
View ArticleLiver Disease Secondary to Intestinal Failure
IFALD is a common and potentially life-threatening condition for patients with SBS requiring long-term PN. There exists the potential for decreasing its incidence by optimizing the composition and the...
View ArticleCD49b, a Major Marker of Regulatory T-Cells Type 1, Predicts the Response to...
The TRANSPEG study was a prospective study to assess the efficacy of antiviral therapy in patients with a recurrent hepatitis C virus (HCV) after liver transplantation. The influence of regulatory...
View ArticleLipopolysaccharide Stimulates p62-Dependent Autophagy-Like Aggregate...
Impairment of autophagy has been associated with liver injury. TLR4-stimulation by LPS upregulates autophagy in hepatocytes, although the signaling pathways involved remain elusive. The objective of...
View ArticleSNP rs8099917 in Gene IL28B Might Be Associated with Risk of Chronic...
Aim. The aim of this study was to characterize the genetic profile of patients with chronic hepatitis C virus (HCV) infection relative to polymorphisms rs12979860 and rs8099917 in gene IL28B and the...
View ArticleExpression of EpCAM Increases in the Hepatitis B Related and the...
Increasing evidence supports the important role of cancer stem cells (CSCs). Many reports suggest that epithelial cell adhesion molecule (EpCAM) is a useful marker for cancer stem cells in...
View ArticleA New Sampling Method for Spleen Stiffness Measurement Based on Quantitative...
In our study, we evaluated the feasibility of a new sampling method for splenic stiffness (SS) measurement by Quantitative Acoustic Radiation Force Impulse Elastography (Virtual Touch Tissue...
View ArticleNonalcoholic Fatty Liver Disease and Hepatocellular Carcinoma
Hepatocellular carcinoma (HCC) incidence is increasing worldwide in recent years. Most HCC cases develop in the presence of advanced chronic liver disease related to chronic hepatitis C virus (HCV)...
View ArticleClinicopathological Factors Affecting Survival and Recurrence after Initial...
We evaluated clinicopathological factors affecting survival and recurrence after initial hepatectomy in non-B non-C (NBNC) hepatocellular carcinoma (HCC) patients with comparison to hepatitis B or C...
View ArticleMicroRNAs in Nonalcoholic Fatty Liver Disease: Novel Biomarkers and...
Nonalcoholic fatty liver disease (NAFLD) is a metabolic-related disorder ranging from steatosis to steatohepatitis, which may progress to cirrhosis and hepatocellular carcinoma (HCC). The influence of...
View ArticleLong Noncoding RNA Plays a Key Role in Metastasis and Prognosis of...
Long noncoding RNAs (lncRNAs) have been attracting immense research interests. However, only a handful of lncRNAs had been thoroughly characterized. They were involved in fundamental cellular processes...
View ArticleRelationship between GH/IGF-1 Axis, Graft Recovery, and Early Survival in...
Background. High levels of IGF-1 have been reported in patients with initial poor function of the graft after liver transplantation (LT). Correlation with other clinical variables or early survival has...
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