Identification of MAD2L1 as a Potential Biomarker in Hepatocellular Carcinoma...
Background. Hepatocellular carcinoma (HCC) is widely acknowledged as a malignant tumor with rapid progression, high recurrence rate, and poor prognosis. At present, there is a paucity of reliable...
View ArticleDiagnostic Value of Serum Chitinase-3-Like Protein 1 for Liver Fibrosis: A...
Background. Serum chitinase-3-like protein 1 (CHI3L1) is a promising marker for diagnosing liver fibrosis. This meta-analysis was carried out to assess the diagnostic performance of serum CHI3L1 for...
View ArticleSilencing the ADAM9 Gene through CRISPR/Cas9 Protects Mice from...
Alcoholic liver injury is a major global public health concern at present. The ADAM9 gene plays a crucial role in the occurrence and development of various liver diseases, but its role in acute...
View ArticleIntervention of Shugan Xiaozhi Decoction on Nonalcoholic Fatty Liver Disease...
Nonalcoholic fatty liver disease (NAFLD) is a chronic liver disease with an increasing incidence rate but few therapies. Shugan Xiaozhi decoction (SX) has demonstrated beneficial effects in treating...
View ArticleAntiviral Therapy for Prevention of Perinatal Hepatitis B Virus Transmission...
Background: Currently, there are few studies on the effect of prophylactic anti-hepatitis B virus (HBV) therapy (AVT) for mother-to-child transmission during pregnancy on postpartum hepatitis flare...
View ArticleAdverse Effects of Bisphenol A on the Liver and Its Underlying Mechanisms:...
BPA is a known endocrine-disrupting agent that is capable of binding to the estrogen receptor and has exhibited adverse effects in many laboratory animal and in vitro studies. Moreover, it also been...
View ArticleOlmesartan Improves Hepatic Sinusoidal Remodeling in Mice with Carbon...
Aim. In mice with liver fibrosis produced by carbon tetrachloride (CCl4), the effects of olmesartan on intrahepatic angiogenesis and sinusoidal remodeling will be evaluated. Methods. By injecting CCl4...
View ArticleGRWR Correlates with the Metabolism of Tacrolimus after Pediatric Living...
Objectives. Tacrolimus is characterized by high pharmacokinetic variability in combination with a narrow therapeutic range. However, influence of donor CYP3A5 genotype and graft-to-recipient body...
View ArticleRosiglitazone Protects against Acetaminophen-Induced Acute Liver Injury by...
Background. Excessive acetaminophen (APAP) use can lead to acute liver injury (ALI) by inducing endoplasmic reticulum stress (ERS). We previously found that pretreatment with the peroxisome...
View Article