Serum Glycocholic Acid-to-Total Bile Acid Ratio Is Independently Associated...
Introduction and Aims. Bile acids play an essential role in the progression of nonalcoholic fatty liver disease (NAFLD). This study was aimed at investigating the association of the serum glycocholic...
View ArticleInterferon-Induced Transmembrane Protein 3 Expression Upregulation Is...
Purpose. Interferon-induced transmembrane protein 3 (IFITM3) is a key signaling molecule regulating cell growth in some tumors, but its function and mechanism in hepatocellular carcinoma (HCC) remain...
View ArticleThe Combination of Shear Wave Elastography and Platelet Counts Can...
Background. Baveno VI criteria, based on liver stiffness (LS) measured by transient elastography and platelet counts (PLT), have been proposed to avoid unnecessary endoscopy screening for high-risk...
View ArticleA Bioinformatic Analysis of Correlations between Polymeric Immunoglobulin...
Objective. This study is aimed at investigating the enriched functions of polymeric immunoglobulin receptor (PIGR) and its correlations with liver fibrosis stage. Methods. PIGR mRNA expression in...
View ArticleSpleen Stiffness Performance in the Noninvasive Assessment of...
Objectives. To investigate the performance of spleen stiffness (SS) by using two-dimensional shear-wave elastography (2D-SWE) for assessing the severity of gastroesophageal varices (GEVs) after...
View ArticlePrevalence and Associated Factors of Portopulmonary Hypertension in Patients...
Background and Aims. There are few studies on the prevalence and clinical characteristics of portopulmonary hypertension (POPH) in patients with portal hypertension. In addition, invasive right heart...
View ArticleIncrease in Free Hepatic Venous Pressure Response to Beta-Blockers Predicts...
Background and Aims. Nonselective beta-blockers (NSBBs) are the main drug to prevent portal hypertension. It could alter free hepatic venous pressure (FHVP); however, the significance is unknown. This...
View ArticleMechanistic Investigation on the Regulation of FABP1 by the IL-6/miR-603...
Background. Abnormal lipid metabolism is closely associated with the invasiveness and metastasis of cancer. Fatty acid-binding proteins (FABPs) play essential roles in lipid metabolism, and miRNAs can...
View ArticleIntegrated Analysis of Long Noncoding RNA Expression Profiles in...
People infected with chronic hepatitis B virus (HBV) might progress to acute-on-chronic liver failure (ACLF) with a high fatality rate. Long noncoding RNAs (lncRNAs) are involved in human diseases, but...
View ArticleDownregulation of snoRNA SNORA52 and Its Clinical Significance in...
Hepatocellular carcinoma (HCC) is one of the most common and aggressive tumors in the world while the accuracy of the present tests for detecting HCC is poor. A novel diagnostic and prognostic...
View ArticleLiver Enzymes and Their Association with Some Cardiometabolic Diseases:...
Objective. According to reports, liver enzymes might play a role in the incidence and development of cardiometabolic diseases such as metabolic syndrome (MetS), hypertension (HTN), and cardiovascular...
View ArticleAntitumor Effect of Lenvatinib Combined with Alisertib in Hepatocellular...
Background and Aim. Although a strong antitumor effect of lenvatinib has been noted for patients with unresectable hepatocellular carcinoma (HCC), its efficacy requires improvement. It is imperative to...
View ArticleAssociation of Low High-Density Lipoprotein Cholesterol Levels with Poor...
Background. Lipid levels become decreased in cirrhotic patients and are correlated with disease severity. In the present study, we investigated the impact of serum high-density lipoprotein cholesterol...
View ArticlePicroside II Improves Severe Acute Pancreatitis-Induced Hepatocellular Injury...
Picroside II is an important ingredient agent in Traditional Chinese medicine and hoped to reduce hepatocellular injury caused by severe acute pancreatitis (SAP). An SAP-induced hepatocellular injury...
View ArticleEffects of Preoperative Oral Carbohydrate on Cirrhotic Patients under...
Preoperative fasting causes significant perioperative discomfort in patients. Preoperative oral carbohydrate (POC) is an important element of the enhanced recovery after surgery protocol, but its...
View ArticleLycopene Ameliorates Liver Inflammation and Redox Status in Mice Exposed to...
Cigarette smoke (CS) is the major cause of preventable death worldwide, and it can also cause damage to extrapulmonary organs, such as the liver, mainly due the generation of reactive oxygen species...
View ArticleTreg/Th17 Cell Balance in Patients with Hepatitis B Virus-Related...
Background. T-helper 17 (Th17) and CD4+CD25+ T-regulatory (Treg) cells play important roles in the pathogenesis of hepatitis B virus-related acute-on-chronic liver failure (HBV-ACLF). This study is...
View ArticleEffects and Mechanism of Oxymatrine Combined with Compound Yinchen Granules...
The aim of the present study was to investigate the effects and mechanism of oxymatrine (OMT) combined with compound yinchen granules (CYG) on the apoptosis of hepatocytes through the Akt/FoxO3a/Bim...
View ArticleMultiple Intestinal Bacteria Associated with the Better Protective Effect of...
Bifidobacterium pseudocatenulatum LI09 could protect rats from D-galactosamine- (D-GalN-) induced liver injury. However, individual difference in the protective effects of LI09 on the liver injury...
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