Porto-Sinusoidal Vascular Disease as the Cause of Portal Hypertension in...
Felty’s syndrome (FS) is a disorder wherein patients with rheumatoid arthritis develop splenomegaly, neutropenia, and in some cases, portal hypertension without underlying cirrhosis. Esophageal...
View ArticleBiliary Microbiota and Bile Acid Composition in Cholelithiasis
Background. A functional interplay between BAs and microbial composition in gut is a well-documented phenomenon. In bile, this phenomenon is far less studied, and with this report, we describe the...
View ArticleCurrent Status and Prospects of Spontaneous Peritonitis in Patients with...
Spontaneous bacterial peritonitis (SBP) is a common cirrhotic ascites complication which exacerbates the patient’s condition. SBP is caused by gram-negative bacilli and, to a lesser extent,...
View ArticleA Novel Prediction Model for Significant Liver Fibrosis in Patients with...
Background. Preventing liver fibrosis from progressing to cirrhosis and even liver cancer is a key step in the treatment of chronic hepatitis B (CHB). This study is aimed at constructing and validating...
View ArticleThe Role of Autophagy and NLRP3 Inflammasome in Liver Fibrosis
Liver fibrosis is an intrinsic repair process of chronic injury with excessive deposition of extracellular matrix. As an early stage of various liver diseases, liver fibrosis is a reversible...
View ArticleValidation of the Combined Model Based on Platelet Count and Albumin to Rule...
Background. The Baveno VI criteria based on platelet count and liver stiffness, measured by transient elastography (TE), have been proposed to rule out high-risk varices (HRV) defined as medium or...
View ArticleCharacterization of an Artificial Liver Support System-Related Vasovagal...
Objective. An artificial liver support system (ALSS) is an effective therapy for patients with severe liver injury. A vasovagal reaction (VVR) is a common complication in various treatment settings but...
View ArticleAn Overview of Lipid Metabolism and Nonalcoholic Fatty Liver Disease
The occurrence of nonalcoholic fatty liver disease (NAFLD) is associated with major abnormalities of hepatic lipid metabolism. We propose that lipid abnormalities directly or indirectly contribute to...
View ArticleProtective Effects of MitoTEMPO on Nonalcoholic Fatty Liver Disease via...
MitoTEMPO, a mitochondrial antioxidant, has protective effects on liver-related diseases. However, the role of MitoTEMPO on nonalcoholic fatty liver disease (NAFLD) and its possible mechanisms are...
View ArticleKupffer Cell-Derived TNF-α Triggers the Apoptosis of Hepatic Stellate Cells...
Purpose. To investigate the roles of ER stress in Kupffer cells (KCs) and KC-derived TNF-α in the apoptosis of hepatic stellate cells (HSCs). Methods. A rat model of liver fibrosis was established....
View ArticleValue of Liver Regeneration in Predicting Short-Term Prognosis for Patients...
Background and Aims. The value of hepatocyte regeneration in predicting the outcomes of hepatitis B-related acute-on-chronic liver failure (HBV-ACLF) is not fully assessed. The present study was aimed...
View ArticleThe Prognosis Analysis of Liver Cirrhosis with Acute Variceal Bleeding and...
Background. Acute variceal bleeding is a major cause of death in liver cirrhosis. This large scale retrospective cohort study aims to analyze the prognosis of patients with cirrhosis and acute variceal...
View ArticleRisk Factors of Portal Vein Thrombosis after Devascularization Treatment in...
Background and Aim. To investigate the incidence of portal vein thrombosis (PVT) after devascularization treatment and to explore the risk factors of perioperative PVT and PVT diagnosed during the...
View ArticleIntestinal Clostridioides difficile Can Cause Liver Injury through the...
This study investigated if intestinal Clostridioides difficile (CD) causes liver injury. Four-week-old male C3H/HeN mice were treated with phosphate-buffered solution (control), CD, diethylnitrosamine...
View ArticleEvaluation of the Combined Application of AFP, AFP-L3%, and DCP for...
The role of α-fetoprotein (AFP) in the surveillance and diagnosis of hepatocellular carcinoma (HCC) has been questioned in recent years due to its low sensitivity and specificity. In addition to AFP,...
View ArticleRecompensation of Decompensated Hepatitis B Cirrhosis: Current Status and...
Liver-function decompensation or hepatocellular carcinoma (HCC) gradually appears after chronic hepatitis B progresses to cirrhosis. Effective antiviral treatment can significantly improve the...
View ArticlelncRNA DLGAP1-AS2 Knockdown Inhibits Hepatocellular Carcinoma Cell Migration...
Objective. DLGAP1-AS2 has been characterized as an oncogenic lncRNA in glioma. Our preliminary microarray analysis revealed the altered expression of DLGAP1-AS2 in hepatocellular carcinoma (HCC), but...
View ArticleFour Autophagy-Related lncRNAs Predict the Prognosis of HCC through...
Abnormally expressed long noncoding RNAs (lncRNAs) have been reported to affect the occurrence and progression of hepatocellular carcinoma (HCC) by modulating the autophagy axis. However, none of...
View ArticlemiR-425-5p Acts as a Molecular Marker and Promoted Proliferation, Migration...
Hepatocellular carcinoma (HCC) is one of the most common and dangerous malignant tumors in China, which causes a large number of deaths every year. MicroRNAs (miRNAs) dysfunction contributes to the...
View ArticleRisk Factors for Hepatocellular Carcinoma Recurrence and Survival after Liver...
Purpose. We aimed to identify prognostic factors for survival and recurrence of hepatocellular carcinoma (HCC) after liver transplantation (LT) for patients with HCC and hepatitis C virus-related...
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