Hepatoprotective and Antiviral Efficacy of Acacia mellifera Leaves Fractions...
The present study investigated the hepatoprotective and anti-HBV efficacy of Acacia mellifera (AM) leaves extracts. The crude ethanolic-extract, including organic and aqueous fractions, were tested for...
View ArticleEffectiveness and Safety of Controlled Venous Pressure in Liver Surgery: A...
Objective. To investigate the effectiveness and safety of controlled venous pressure in liver surgery and further to compare the clinical outcomes of low central venous pressure by infrahepatic...
View ArticleLiver Failure Impairs the Intrahepatic Elimination of Interleukin-6, Tumor...
The strategic location of the liver and its metabolic activity make it a key organ regulating homeostasis. Our purpose was to examine its participation in removal of cytokines: interleukin-6 (Il-6),...
View ArticleAntioxidative Role of Hatikana (Leea macrophylla Roxb.) Partially Improves...
This research investigated the protective role of Leea macrophylla extract on CCl4-induced acute liver injury in rats. Different fractions of Leea macrophylla (Roxb.) crude extract were subjected to...
View ArticleA Novel Matrine Derivative WM130 Inhibits Activation of Hepatic Stellate...
Activation of hepatic stellate cells (HSCs) is a critical event in process of hepatic fibrogenesis and cirrhosis. Matrine, the active ingredient of Sophora, had been used for clinical treatment of...
View ArticleTissue Remodelling following Resection of Porcine Liver
Aim. To study genes regulating the extracellular matrix (ECM) and investigate the tissue remodelling following liver resection in porcine. Methods. Four pigs with 60% partial hepatectomy- (PHx-)...
View ArticleRotavirus Infects Human Biliary Epithelial Cells and Stimulates Secretion of...
Biliary atresia (BA) is an infantile inflammatory cholangiopathy of unknown etiology although epidemiologic studies and animal models utilizing rotavirus (RV) have suggested a role for viral...
View ArticleFructose-Drinking Water Induced Nonalcoholic Fatty Liver Disease and...
Background. Nonalcoholic fatty liver disease (NAFLD) is one of the complications of the metabolic syndrome. It encompasses a wide range of disease spectrum from simple steatosis to liver cirrhosis....
View ArticleDrug Induced Steatohepatitis: An Uncommon Culprit of a Common Disease
Nonalcoholic fatty liver disease (NAFLD) is a leading cause of liver disease in developed countries. Its frequency is increasing in the general population mostly due to the widespread occurrence of...
View ArticleDoes Diacylglycerol Accumulation in Fatty Liver Disease Cause Hepatic Insulin...
Numerous studies conducted on obese humans and various rodent models of obesity have identified a correlation between hepatic lipid content and the development of insulin resistance in liver and other...
View ArticleImprovement of BMI after Lifestyle Intervention Is Associated with...
Background. Noninvasive tools to diagnose nonalcoholic fatty liver disease (NAFLD), including transient elastography (TE) and enhanced liver fibrosis panel (ELF), have only been evaluated in children...
View ArticleAssociation of Nonalcoholic Fatty Liver Disease with Subclinical...
In the last 20 years, nonalcoholic fatty liver disease (NAFLD) has become the leading cause of chronic liver disease worldwide, primarily as a result of the epidemic of obesity. NAFLD is strongly...
View ArticleThe Potential Role of Iron and Copper in Pediatric Obesity and Nonalcoholic...
Obesity is a rapidly growing health problem and is paralleled by a multitude of comorbidities, including nonalcoholic fatty liver disease (NAFLD). NAFLD has become the most common chronic liver disease...
View ArticleNonalcoholic Steatohepatitis: Involvement of the Telomerase and...
Nonalcoholic steatohepatitis or NASH is an excessive accumulation of fat in hepatocytes accompanied by inflammation and hepatic injury. Proinflammatory molecules such as IL-17, CCL20, S100A8, S100A9,...
View ArticleGenetic Factors in the Pathogenesis of Nonalcoholic Fatty Liver and...
Liver fat accumulation generally related to systemic insulin resistance characterizes nonalcoholic fatty liver disease (NAFLD), which in the presence of nonalcoholic steatohepatitis (NASH) can progress...
View ArticleHow Far Can We Go with Laparoscopic Liver Resection for Hepatocellular...
Although the reports of laparoscopic major liver resection are increasing, hepatocellular carcinomas (HCCs) close to the liver hilum and/or major hepatic veins are still considered contraindications....
View ArticleTransarterial Embolization for Hepatocellular Carcinoma: A Comparison between...
Transarterial chemoembolization (TACE) and transarterial embolization (TAE) have improved the survival rates of patients with unresectable hepatocellular carcinoma (HCC); however, the optimal TACE/TAE...
View ArticlePredictors for Early Identification of Hepatitis C Virus Infection
Hepatitis C virus (HCV) infection can cause permanent liver damage and hepatocellular carcinoma, and deaths related to HCV deaths have recently increased. Chronic HCV infection is often undiagnosed...
View ArticleLentivirus-Mediated siRNA Targeting ER-α Inhibits Tumorigenesis and Induces...
Background and Objectives. Estrogen receptor-α (ER-α) plays important roles in hepatocarcinogenesis. Recent studies have shown that ER-α could lead to cell cycle progression or inhibition of apoptosis....
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