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Sex, Age, and BMI Modulate the Association of Physical Examinations and Blood...

Objective. Previous studies have shown that some metabolic risk factors are related to nonalcoholic fatty liver disease (NAFLD). This retrospective study was performed to investigate the associations...

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Hepatoprotective Effect of Jianpi Huoxue Formula on Nonalcoholic Fatty Liver...

In parallel with the prevalence metabolic syndrome, nonalcoholic fatty liver disease (NAFLD) has become the most common chronic liver disease in most countries. It features a constellation of simple...

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Alcoholic and Nonalcoholic Liver Disease: Diagnostic Assessment and...

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Transarterial Chemoembolization (TACE) Combined with Sorafenib in Treatment...

Objectives. Hepatocellular carcinoma (HCC) with portal vein tumor thrombus (PVTT) remains a challenge in management. Transarterial chemoembolization (TACE) has been used for patients with PVTT but...

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Intraoperative Hepatic Blood Inflow Can Predict Early Acute Kidney Injury...

Purpose. Acute kidney injury (AKI) is a major and severe complication following donation-after-circulatory-death (DCD) liver transplantation (LT) and is associated with increased postoperative...

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Metabolic Comorbidities and Risk of Development and Severity of Drug-Induced...

The incidence and rates of diagnosis of drug-induced liver injury (DILI) have been increasing in recent years as findings from basic research and the examination of clinical databases reveal...

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Elevated Preoperative Serum CA125 Predicts Larger Tumor Diameter in Patients...

Aim. Little is known about the association between cancer antigen 125 (MUC16/CA125) concentrations and tumor diameter of patients with hepatocellular carcinoma (HCC) and low AFP levels. To fill this...

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Identification of Key Transcription Factors AP-1 and AP-1-Dependent miRNAs...

Liver ischemia/reperfusion (I/R) injury is a complex and common clinical disease with limited therapeutic options. The aim of our study was to discover the candidate target genes in liver I/R injury...

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Bone Marrow-Derived Mesenchymal Stem Cell Potential Regression of Dysplasia...

Objectives. Assessing the therapeutic efficacy of superparamagnetic iron oxide nanoparticles (SPIO) labeled bone marrow-derived mesenchymal stem cells (BM-MSCs) on experimental liver fibrosis and...

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Carvedilol Inhibits Angiotensin II-Induced Proliferation and Contraction in...

Aim. Carvedilol is a nonselective beta-blocker used to reduce portal hypertension. This study investigated the effects and potential mechanisms of carvedilol in angiotensin II- (Ang II-) induced...

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HIF-1-miR-219-SMC4 Regulatory Pathway Promoting Proliferation and Migration...

This paper aims to investigate the function of structural maintenance of chromosome 4 (SMC4) in the progression of hepatocellular carcinoma (HCC) under hypoxic condition. In this study, we found that...

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Systematic Review with Meta-Analysis: Efficacy and Safety of Direct-Acting...

Direct-acting antivirals (DAAs) are modern treatments for chronic hepatitis C infection, but majority of available evidence on its treatment effect covers genotypes 1 to 4. Therefore, the efficacy and...

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Pharmacological Benefits and Risk of Using Hormones in Organ Perfusion and...

For several years, research has been carried out on the effectiveness of solutions for perfusion and preservation of organs, including the liver. There is a search for an optimal pharmacological...

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Advances in Gut Microbiota of Viral Hepatitis Cirrhosis

Although gut dysbiosis appears in 20%–75% of cirrhotic patients, there are limited data on microbiota profiles in viral hepatitis cirrhotics and its role in progression to cirrhosis. Further...

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Artificial Liver Support System Improves Short-Term Outcomes of Patients with...

Background. Hepatitis B virus-associated acute-on-chronic liver failure (HBV-ALCF) is a complicated syndrome with extremely high short-term mortality. The artificial liver support system (ALSS) may...

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Diagnosis System for Hepatocellular Carcinoma Based on Fractal Dimension of...

Background and Aims. Hepatocellular carcinoma (HCC) remains a leading cause of death by cancer worldwide. Computerized diagnosis systems relying on novel imaging markers gained significant importance...

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Hepatocellular Carcinoma: Carcinogenesis, Establishment, Progression, and...

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Natural Killer Cell Function and Dysfunction in Hepatitis C Virus Infection

Viruses must continually adapt against dynamic innate and adaptive responses of the host immune system to establish chronic infection. Only a small minority (~20%) of those exposed to hepatitis C virus...

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The Effects of Apigenin on the Expression of Fas/FasL Apoptotic Pathway in...

Background. The aim of this experimental study was to investigate the role of apigenin in liver apoptosis, in an experimental model of hepatic ischemia-reperfusion in rats. Materials and Methods....

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Hepatic Chemerin and Chemokine-Like Receptor 1 Expression in Patients with...

Introduction. Chemerin seems to be involved in pathogenesis of chronic hepatitis C (CHC). Hepatic expressions of chemerin and its receptor, chemokine receptor-like 1 (CMKLR1), in CHC have not been...

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