Lipometabolism and Glycometabolism in Liver Diseases
The liver is the mainly metabolic organ in the body especially in lipometabolism and glycometabolism. Carbohydrates and fats disorders can result in insulin resistance in the liver. Metabolic imbalance...
View ArticleDoxazosin and Carvedilol Treatment Improves Hepatic Regeneration in a Hamster...
Regulation of the mechanisms of fibrosis is an important goal in the treatment of liver cirrhosis. One mechanism is the participation of hepatic stellate cells in fibrogenesis when activated by...
View ArticleThe Removal of HBV in Plasma by Extracorporeal Immunoadsorption from Plasma:...
Objective. To establish a novel HBV specific immunoadsorbent for the removing of HBV particles. Methods. The anti-HBsAg monoclonal antibody was immobilized on sepharose beads to produce a sepharose...
View ArticlePrognostic Value of Lactate Dehydrogenase in Patients with Hepatocellular...
Background. Previous studies have shown the prognostic value of lactate dehydrogenase (LDH) in hepatocellular carcinoma (HCC), but the results are not persuasive. Therefore, the purpose of our study...
View ArticleGut Microbiota-Derived Mediators as Potential Markers in Nonalcoholic Fatty...
Nonalcoholic fatty liver disease (NAFLD) is a common, multifactorial, and poorly understood liver disease whose incidence is globally rising. During the past decade, several lines of evidence suggest...
View ArticleNonalcoholic Fatty Liver Disease Aggravated the Severity of Acute...
Background and Aim. The incidence of nonalcoholic fatty liver disease (NAFLD) as a metabolic disease is increasing annually. In the present study, we aimed to explore the influence of NAFLD on the...
View ArticleTransient Elastography and Ultrasonography: Optimal Evaluation of Liver...
Background and Aims. Concordance between transient elastography (TE) and ultrasonography (US) in assessing liver fibrosis in patients with chronic hepatitis B (CHB) and concurrent nonalcoholic fatty...
View ArticleRole of Noncoding RNA in Development of Nonalcoholic Fatty Liver Disease
Nonalcoholic fatty liver disease (NAFLD) is increasing in prevalence globally, but little is known about its specific molecular mechanisms. During the past decade, noncoding RNAs (ncRNAs) have been...
View ArticleCharacteristics, Risk Factors, and Adverse Outcomes of Hyperkalemia in...
Background. Hyperkalemia is a serious complication in cirrhotic patients. However, the clinical characteristics, risk factors, and its impact on the outcomes in acute-on-chronic liver failure (ACLF)...
View ArticleSerum Cystatin C Predicts Mortality in HBV-Related Decompensated Cirrhosis
Background. Some studies have reported that renal dysfunction is associated with poor prognosis in cirrhotic patients. Serum cystatin C (CysC) is an accurate biomarker for early renal dysfunction. This...
View ArticleEtifoxine, a TSPO Ligand, Worsens Hepatitis C-Related Insulin Resistance but...
Etifoxine, an 18 kDa translocator protein (TSPO) agonist for the treatment of anxiety disorders in clinic, may be able to cause acute liver injury or cytolytic hepatitis. TSPO has been demonstrated to...
View ArticlePentraxin 3 Detects Clinically Significant Fibrosis in Patients with Chronic...
Pentraxin 3 (PTX3) plays a pathogenic role in experimental models of chronic liver injury and contributes to the progression of fibrosis. The detection of advanced fibrosis (METAVIR F≥3) is important...
View ArticleFecal Microbiota of Diarrhea-Predominant Irritable Bowel Syndrome Patients...
Effects of the microbiome associated with diarrhea-predominant irritable bowel syndrome (IBS-D) on the gut have been reported, but no study has reported the effects of the IBS-D gut microbiome on the...
View ArticleAssociation between Alanine Aminotransferase and Growth Hormone: A...
Objective. This study aimed to examine the relationship between serum alanine aminotransferase (ALT) and growth hormone (GH) in children and adolescents with short stature. Methods. In this...
View ArticleBalloon-Assisted Percutaneous Transhepatic Antegrade Embolization with...
Aims. To evaluate the safety and effectiveness of percutaneous transhepatic antegrade embolization (PTAE) with 2-octyl cyanoacrylate assisted with balloon occlusion of the left renal vein or...
View ArticleResearch Progress on the Animal Models of Drug-Induced Liver Injury: Current...
Drug-induced liver injury (DILI) is a major concern in clinical studies as well as in postmarketing surveillance. It is necessary to establish an animal model of DILI for thorough investigation of...
View ArticleShenqi Fuzheng Injection (SFI) Enhances IFN-α Inhibitory Effect on...
Shenqi Fuzheng Injection (SFI) is a traditional Chinese medicine injection with anticancer properties and is mainly composed of ginseng and astragalus. Its efficacy has been confirmed in clinical...
View ArticleNoninvasive Indirect Markers of Liver Fibrosis in Alcoholics
The aim of this study was to evaluate the diagnostic values of noninvasive indirect markers of liver fibrosis: APRI, GAPRI, Forns, FIB-4, Age-Platelet, and Hepascore in alcoholics. Blood samples were...
View ArticleThe Impact of Steatosis on the Outcome of Liver Transplantation: A Meta-Analysis
Background and Aims. Liver transplantation is one of the most effective treatments for end-stage liver disease as well as for cases of acute liver failure. Facing organ donor shortage, liver transplant...
View ArticleThe Use of Antifibrotic Recombinant nAG Protein in a Rat Liver Fibrosis Model
Objectives. The “nAG” protein is the key protein mediating the regeneration of amputated limbs in salamanders. The senior author (MMA) developed the original hypothesis that since “nAG” is a...
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